Types of Research and Training Programs

Updated December 8, 2014

This list is an NIAMS-specific excerpt from the NIH list of activity codes.


Fellowship Programs ( F )
Research Career Awards ( K )
Research Programs and Centers ( P )
Research Project Grants ( R )
Training Programs ( T )
Cooperative Agreements ( U )
Research-Related Programs ( S )
Supplement Programs
Loan Repayment Programs
Formula Grants (X)

 

Fellowship Programs ( F )

Note: For supplements to funded research grants to support training and career development of under-represented minorities, people from socioeconomically disadvantaged backgrounds or persons with disabilities please see Supplement Programs.
F30 Predoctoral MD/PhD and Other Dual Doctoral Degree Individual National Research Service Award
To provide predoctoral support for individual MD/PhD and other dual doctoral degree students to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required.
Duration: Up to 6 years
Commitment: Full-time research fellowship
Provisions: See FY2013 Guide Notice
Institutional Allowance: See FY2013 Guide Notice
Applications Due: Standard dates
See active F30 funding opportunities

 

F31 Predoctoral Individual National Research Service Award
To provide predoctoral support of research leading to the Ph.D. or equivalent research degree for individuals to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required.
Duration: Up to 5 years
Commitment: Full-time research fellowship
Provisions: See FY2013 Guide Notice
Institutional Allowance: See FY2013 Guide Notice
Applications Due: Standard dates
See active F31 funding opportunities

 

F32 Postdoctoral Individual National Research Service Award
To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Requires M.D. or Ph.D. or equivalent.
Duration: Up to 3 years
Commitment: Full-time research fellowship
Provisions: See FY2013 Guide Notice
Institutional Allowance: See FY2013 Guide Notice
Applications Due: Standard dates
See active F32 funding opportunities

 

F33 Senior Fellowship
Fellowships to provide opportunities for experienced scientists to make major changes in the direction of research careers, to broaden scientific background, and to acquire new research capabilities regarding arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Level: At least 7 years postdoctoral (this is a "sabbatical" award)
Duration: Up to 2 years
Commitment: Full-time research fellowship
Provisions: See FY2009 NIH Guide Notice (no fringe benefits)
Institutional Allowance: See FY2009 NIH Guide Notice
Applications Due: Standard dates
See active F33 funding opportunities

 

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Research Career Awards ( K )

Note: For supplements to funded research grants to support training and career development of under-represented minorities, people from socioeconomically disadvantaged backgrounds or persons with disabilities please see Supplement Programs
K01 Mentored Research Scientist Development Awards
To provide research scientists with an additional period of sponsored research experience as a way to gain expertise in a research area new to the applicant or in an area that would demonstrably enhance the applicant's scientific career. These awards are generally reserved for individuals interested in switching to a new research field, for individuals who have interrupted their career because of illness or pressing family care responsibilities, or for faculty at minority institutions who wish to enhance their capacity for independent research.
Duration: Up to 5 years
Provisions: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $20,000.
Applications Due: Standard dates
See active K01 funding opportunities

 

K02 Independent Research Scientist Development Awards
NIAMS no longer participates in this grant mechanism.

 

K08 Mentored Clinical Scientist Development Investigator Awards
To support clinicians who need an intensive period of mentored research experience.
Duration: Up to 5 years
Provisions: *Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $20,000.
Applications Due: Standard dates
*Please see NOT-AR-07-001
See active K08 funding opportunities

 

K12 Physician Scientist Award (Program) (PSA)
For support to a newly trained clinician appointed by an institution for development of independent research skills and experience in a fundamental science within the framework of an interdisciplinary research and development program.
Contact: Joan Davis Nagel, MD MPH
Applications Due: 10/21/2011
Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-11-002.html#_Section_VII._Agency_1
See active K12 funding opportunities

 

K23 Mentored Patient-Oriented Research Career Development Award
To support supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators focusing on patient-oriented research. Candidates must have completed their specialty and, if applicable, subspecialty training prior to receiving an award.
Duration: 3 to 5 years
Provisions: *Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $25,000.
Applications Due: Standard dates
*Please see NOT-AR-07-001
See active K23 funding opportunities

 

K24 Midcareer Investigator Award in Patient-Oriented Research
To support protected time for clinicians to allow them time for patient-oriented research and to act as mentors for beginning clinical investigators. Candidates must have completed their specialty training within 15 years of submitting the application. Candidates must be working in a research environment, conducting patient-oriented research, and have independent research support.
Duration: 3 to 5 years.
Provisions: Support up to 50% of the NIH salary cap ($196,700 in FY 2009) is provided and up to $50,000 in selected research expenses.
Applications Due: Standard dates
See active K24 funding opportunities

 

K25 Mentored Quantitative Research Career Development Award
To support supervised study and research for investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on biomedical research. This mechanism is aimed at research-oriented scientists with experience at the level of junior faculty who have the potential to integrate their expertise with biomedicine and to develop into productive investigators.
Duration: 3 to 5 years.
Provisions: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $25,000.
Applications Due: Standard dates
See active K25 funding opportunities

 

K99/R00 NIH Pathway to Independence (PI) Award
The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components, a mentored (K99) phase that can last up to 2 years and an independent (R00) phase, which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research, and apply for an independent research faculty position, during the mentored phase of the award. Activation of the independent award phase is administrative, and is contingent upon the investigator securing an independent research position. Eligible candidates will have no more than 4 years of postdoctoral research at the time of application (initial or amended). Award recipients are expected to obtain R01 support during the independent phase of the award.
Provisions: For mentored candidates in an extramural institution, NIAMS will provide up to $50,000 per year for salary support (up to $75,000 per year for applicants with an M.D. degree), plus fringe, and up to $20,000 for research support costs. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions.
See active K99/R00 funding opportunities

 

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Research Programs and Centers ( P )

P01 Research Program Project Grants

The NIAMS is no longer accepting applications for the P01.


Applications Due: 

 

P30 Research Core Centers
To promote a cooperative interaction among basic science and clinical investigators in a manner that will enrich the effectiveness of ongoing research and promote new research. Any institution or consortium with an active program of excellence in basic and clinical biomedical research in skin diseases, musculoskeletal disorders or rheumatic diseases, may qualify for support through a Core Center. A strong biomedical research base is the prerequisite for establishment of a Core Center and an important component in considering continued funding of an established center. The components of a core center include 2 or more research cores and an administrative core that includes an Enrichment Program.
Duration: 5 years
Budget Cap: $400,000 direct costs

Additional Information: suggested exhibits for P30 applications — PDF format   

Core Centers for Musculoskeletal Biology and Medicine: Letters of intent due May 31, 2013; Applications Due July 1, 2013

Skin Diseases Research Core Centers: Letters of intent due August 20, 2013; Applications Due September 20, 2013

 

P50-CORT Centers of Research Translation (CORT)
Contact: Ms. Justine Buschman
To promote translational research through a multidisciplinary approach on a disease specific theme. A CORT should have both basic and clinical research components.
Duration: 5 years
Budget Cap: $1,000,000 direct costs
Applications Due: By RFA only
Additional Information: CORT Guidelines - PDF format   /  CORT FAQs  -  PDF format

 

P50-ORWH Specialized Centers of Research on Sex and Gender Factors Affecting Women’s Health (SCOR)
Contact: Dr. Bernadette Tyree
The Office of Research on Women's Health (ORWH) serves as a focal point for women's health research at the NIH. The ORWH promotes, stimulates, and supports efforts to improve the health of women through biomedical and behavioral research. ORWH works in partnership with the NIH Institutes as well as the Food and Drug Administration (FDA) to ensure that women's health research is part of the scientific framework at NIH and throughout the scientific community. The ORWH announces the Specialized Centers of Interdisciplinary Research on Sex and Gender Factors Affecting Women's Health (SCOR) program. These centers will provide new opportunities for interdisciplinary approaches to advancing studies on how sex and gender factors affect women's health. Each SCOR should develop an interdisciplinary research agenda bridging basic and clinical research on sex/gender factors underlying a priority women’s health issue.
Duration: 5 years
Budget Cap: $750,000 direct costs
Applications Due: By RFA only

 

P60 Multidisciplinary Clinical Research Centers (MCRC)
Contact: Ms. Justine Buschman
To support a full range of outstanding multidisciplinary clinical research in the areas of arthritis and musculoskeletal and skin diseases. Each MCRC is organized around a methodology core and must include a minimum of two highly meritorious projects. The projects and overall Center can be focused on one or more diseases/conditions. The methodology core must demonstrate that it can provide support for multidisciplinary approaches for clinical projects within and outside the MCRC. The methodology core is the foundation of the Center, providing key support for development and implementation of clinical projects. The director of the MCRC, aided by an executive committee and the methodology core, provides leadership to assure a rigorous research approach and to focus all research projects on critical issues relevant to disease prevention or to assessment and/or to improve outcomes of patients with chronic diseases/conditions within the mission of the NIAMS. The MCRCs will build on a meritorious research base and are expected to leverage existing institutional infrastructure resources.
Duration: 5 years
Budget Cap: $800,000 direct costs
Applications Due: By RFA only
Additional Information: MCRC Guidelines - PDF format   WORD format

 

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Research Project Grants ( R )

R01 Research Grants
Definition and other information provided under the R01 Guidelines related links.
Additional Information: Modular Grants

NIAMS Building Interdisciplinary Research Team (BIRT) Competitive Revision Awards (R01 only)
Contact: Carl Baker and Fei Wang
To promote building NEW interdisciplinary teams among independent investigators that pursue a clear and significant scientific opportunity in an area of shared interest of relevance to NIAMS. At least one investigator must have an active NIAMS-supported R01.
Duration: 1 year
Budget Cap: $100,000 direct costs
Letters of intent due: October 15, 2012 ; June 17, 2013; June 16, 2014
Applications due: November 15, 2012 ; July 15, 2013; July 15, 2014
Additional information: BIRT FAQs PDF Format
See active R01 funding opportunities

 

R03 Small Research Grants
The NIAMS Small Grant Program for New Investigators (R03) is intended for researchers that need funding to develop preliminary data for their first R01 application. These grants support studies related to arthritis, musculoskeletal or skin diseases or disorders.
Duration: No more than 3 years, not renewable.
Budget Cap: $50,000/yr. direct costs.
Applications Due: 03/20/2012, 07/20/2012, 11/20/2012, 03/20/2013, 07/19/2013, 11/20/2013, 03/20/2014, 07/21/2014, 11/20/2014, 3/20/2015
NIAMS also participates in other R03 program announcements for specific topics of research.
See active R03 funding opportunities

 

R13/U13 Conference and Scientific Meeting Grants
Contact: Dr. Xibin Wang
Definition and other information provided under the R13 / U13 Guidelines related links.
See active R13/U13 funding opportunities

 

R15 AREA Grants
Definition and other information provided under the R15 Guidelines related links.
See active R15 funding opportunities

 

R21 NIAMS High Innovation Exploratory/Developmental Research Grant Program
NIAMS accepts applications in response to PA-10-069 "NIH Exploratory/Developmental Research Grant Program (Parent R21)" proposing studies related to arthritis, musculoskeletal or skin diseases or disorders.

Potential applicants are strongly encouraged to discuss the suitability of the project for this program announcement with the NIAMS Program Director for that research topic area.

See NOT-AR-10-023 for additional information regarding NIAMS support for innovative research using R21 grants.

In making funding decisions on R21 applications, NIAMS will place a higher priority on projects that are:
  • Innovative, ground-breaking projects with potential for significant impact;
  • Projects that involve novel technology or tool development, and have the potential to significantly accelerate research fields;
  • Projects that propose the novel application of methods, technologies, or conceptual approaches from outside biomedical science to a research problem in the NIAMS mission area.
Projects that will be considered a lower priority include:
  • Projects specifically to develop preliminary data for longer-term projects in a well established research area;
  • New investigator starter grants;
  • Pilot projects that do not exhibit a high degree of innovation.

Contact: See NIAMS supported scientific areas and contact information for the Program Directors.
Duration: 2 years
Budget Cap: $275,000 direct costs spread over two years
Applications Due: Standard dates
Projects of limited time and scope that do not meet these characteristics of innovative, ground-breaking research should consider applying for a small Research Project Grant (Parent R01). For example, an R01 for two or three years at $100,000 direct cost per year could support a pilot project.

New investigators are encouraged to apply for an R01 (see NOT-OD-09-013, "Revised New and Early Stage Investigator Policies) or an R03 (see NIAMS Small Grant Program for New Investigators).

Preference in funding decisions for R21 grants will be given to projects within the NIAMS mission areas that are especially innovative, ground-breaking and have a high potential impact on these fields.

NIAMS also has funding opportunities for R21 grants on specific topics. The goal of supporting innovative, ground-breaking, highly significant research with the R21 activity code also applies to these funding opportunities.
See active R21 funding opportunities

 

R25 Education Projects
For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation. In this case, the Clinical Research Education and Career Development (CRECD) grant awards support development and implementation of curriculum-dependent programs in minority institutions to train selected doctoral and postdoctoral candidates in clinical research leading to a Master of Science in Clinical Research or Master of Public Health in a clinically relevant area. A successful program will result in an accredited master's degree program to produce trained and independent clinical researchers who can become engaged in conducting translational and/or patient-oriented research projects.
Duration: Up to 5 years to a minority institution
Budget Cap: $500,000/yr direct costs
Applications Due: By RFA only
See active R25 funding opportunities

 

R41/R42 Small Business Technology Transfer (STTR) Program
The STTR program is a set-aside program designed to support innovative research that has the potential for commercialization of the subject research conducted cooperatively by a small business concern and a research institution. Innovation and the potential for commercialization are two important aspects of the review criteria considered in the scientific and technical merit evaluation process. At least 40 percent of the research project is to be conducted by the small business concern, and at least 30 percent of the work is to be conducted by the single, partnering research institution.

Phase I (R41) is normally provided for one year/$150,000, which includes direct cost, facilities and administrative cost (F&A/indirect), and fee. The F&A/indirect cost maximum is 40%, if no current negotiated rate.

Phase II (R42) is normally two years/$1,000,000, which includes direct cost, F&A/indirect cost, and fee. The F&A/indirect cost maximum is 40% or current negotiated rate. The applicant may negotiate with NIH.

A reasonable fee, not to exceed 7% of total costs (direct and indirect) for each Phase (I and II) of the project, can be requested solely to small business concerns receiving awards under the STTR program.

With appropriate justification from the applicant, Congress will allow awards to exceed the normal guidelines by up to 50% ($225,000 for Phase I and $1,500,000 for Phase II). Applicants are strongly encouraged to contact the program officials prior to submitting any application in excess of the guidelines.
Contact: Xibin Wang wangx1@mail.nih.gov
Applications Due: April 5, August 5, December 5
Additional Information: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs

 

R43/R44 Small Business Innovation Research (SBIR) Program
The SBIR program is a set-aside program designed to support innovative research that has the potential for commercialization of the subject research conducted by a small business concern. Innovation and the potential for commercialization are two important aspects of the review criteria considered in the scientific and technical merit evaluation process.

Phase I (R43) is normally provided for six months/$150,000, which includes direct cost, facilities and administrative (F&A/indirect) cost and fee. The F&A/indirect cost maximum is 40%, if no current negotiated rate. In Phase I, normally, a minimum of two-thirds or 67% of the research or analytical effort must be carried out by the small business concern. The total amount of all consultant and contractual arrangements to third parties for portions of the scientific and technical effort generally may not exceed 33% of the total amount requested.

Phase II (R44) is normally two years/$1,000,000, which includes direct cost, F&A/indirect cost and fee. The F&A/indirect cost maximum is 40% or current negotiated rate. The applicant may negotiate with NIH. In Phase II, normally, a minimum of one-half or 50% of the research or analytical effort must be carried out by the small business concern. The total amount of consultant and contractual arrangements to third parties for portions of the scientific and technical effort generally may not exceed 50% of the total Phase II amount requested.

A reasonable fee, not to exceed 7% of total costs (direct and indirect) for each Phase (I and II) of the project, can be requested solely to small business concerns receiving awards under the SBIR program.

With appropriate justification from the applicant, Congress will allow awards to exceed the normal guidelines by up to 50% ($225,000 for Phase I and $1,500,000 for Phase II). Applicants are strongly encouraged to contact the program officials prior to submitting any application in excess of the guidelines.
Contact: Xibin Wang wangx1@mail.nih.gov
Applications Due: April 5, August 5, December 5
Additional Information: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs
See active R43/R44 funding opportunities

 

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Training Programs ( T )

T32 Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants
NIAMS offers these grants to enable institutions to make NRSAs for predoctoral and postdoctoral research training to individuals selected by them in the fields of arthritis, muscle, bone, musculoskeletal, and/or skin diseases.
Duration: 5-year institutional grant (renewable).
Applications Due: May 25
Additional Information: NIAMS T32 Program
See active T32 funding opportunities

 

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Cooperative Agreements ( U )

U01 Research Project Cooperative Agreements
These are agreements between NIH and the award recipient in which the NIH acts as the partner in the research effort for projects similar to grants.
See active U01 funding opportunities

 

U34 Clinical Planning Grant Cooperative Agreement
This cooperative agreement would provide support, substantial Federal programmatic involvement, and technical assistance for the initial development of a clinical trial. Also, it would include the establishment of the research team; the development of tools for data management and oversight of the research; the development of a trial design and other essential elements of the study, such as the protocol, recruitment strategies, and procedure manuals; and to collect feasibility data.
See active U34 funding opportunities

 

U44 Small Business Innovation Research (SBIR) Cooperative Agreements - Phase II
To support in-depth development of R&D ideas whose feasibility has been established in Phase I and that are likely to result in commercial products or services (also Fast Track).
Contact: Xibin Wang (SBIR/STTR)

 

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Research-Related Programs ( S )

S06 Minority Biomedical Research Support - MBRS
To strengthen the biomedical research and research training capability of ethnic minority institutions, and thus establish a more favorable milieu for increasing the involvement of minority faculty and students in biomedical research.
Applications Due: 08/16/2013

 

S10 Biomedical Research Support Shared Instrumentation Grants (NCRR)
To make available to institutions with a high concentration of NIH extramural research awards, research instruments which will be used on a shared basis.

 

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Supplement Programs

Note: Supplemental applications accepted year round except from July 1 through October 1
Administrative Supplements

The National Institutes of Health (NIH) has recently posted guidance regarding administrative supplements. The announcement informs principal investigators (PIs) holding specific types of NIH research grants that funds may be available for administrative supplements.

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) allows three primary types of administrative supplements:

  • Diversity Supplements: See FOA here for guidelines: http://grants.nih.gov/grants/guide/pa-files/PA-12-149.html
    • For Individuals in Postdoctoral Training: The total salary and fringe benefits (combined) must be in accordance with the salary structure of the grantee institution and consistent with the level of effort, but may not exceed $50,000 per year.
  • Reentry Supplements: See FOA here for guidelines: http://grants.nih.gov/grants/guide/pa-files/PA-12-150.html
  • Generic Administrative Supplements: See FOA here for guidelines: http://grants.nih.gov/grants/guide/pa-files/PA-14-077.html

    These supplements are restricted to budgetary requests arising from unusual or exceptional circumstances (e.g., natural disasters) and emergencies. The NIAMS will only consider requests for administrative supplements to provide support for the accomplishment of the original aims of a project in circumstances in which these unanticipated costs have arisen, placing the overall success of the project in question. Requests related to lapses in funding and possible new directions will not be considered. The NIAMS has very limited funds for such supplements, and approves such requests infrequently.

To award new funds for a significant expansion of a project’s scope a grantee must apply for a competing revision and undergo peer review.

Before proceeding with any supplement request, PIs are advised to contact their program officer to discuss scientific need and their grants management specialist to discuss budget and policy issues.

 

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Loan Repayment Programs

LRP   Loan Repayment Programs
Contact: Laura K. Moen, Ph.D.
LRP Information Center: 866-849-4047 or lrp@nih.gov

The NIAMS welcomes applications to the NIH Loan Repayment Program. We are interested in applications that meet the eligibility requirements for either the Clinical Research Program or the Pediatric Research Program. We are particularly interested in applications from physician-scientists. Please visit http://www.lrp.nih.gov for eligibility information, application instructions and more.